A Head-to-head Comparison  Previous studies have shown that after a diagnosis of early-stage breast cancer, a lumpectomy followed by WBI decreases the risk of the cancer returning in the same breast.  But many women do not receive the recommended radiation therapy for various reasons, including the inconvenience of traveling to a distant treatment center.  By delivering larger individual does of radiation across fewer treatment sessions, APBI has emerged as an alternate approach to WBI.  Studies have shown that by treating the area of the breast in the vicinity of the original tumor,  APBI can reduce recurrences.  The new trials provide head-to-head comparisons of the two approaches with long-term follow-up.  In the US study, for instance, more than 95% of participants in each treatment group-those receiving either WBI or APBI-did not have a recurrence at a median follow-up of 10 years after their treatment ended.  Investigators with the Canadian Rapid trial reported similar results, although the median follow-up was shorter.  In both studies-and in both treatment arms-the outcomes overall were extremely good,”said Larissa Korde, M.D., of NCI’s Cancer Therapy Evaluation Program.  Patients with early-stage breast cancer, she continued, “can use this information to decide whether APBI is the right course for them individually.” Source: NCI