How Alzheimer’s Damage Happens

26 Apr

Two changes in the brain are the hallmark of Alzheimer’s.

The first is when a protein called beta-amyloid begins to cluster outside neurons in sticky patches known as plaques.  These plaques are believed to block signaling between neurons, or even kill them.

A second change relates to tau, a protein within neurons. Tau proteins stabilize structures (microtubules) inside neurons that help transport nutrients. When tau proteins fall off  the microtubules, those microtubules collapse and the tau proteins become tangled up. Brain disaster follows: The nerve cell’s transit system shuts down, and the cell is kaput.

Source: The Good Life magazine Dr. Oz April 2017

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