LDL & Heart Disease

10 Nov

We know that LDL is the main carrier of cholesterol in the blood, and it enters into the walls of major arteries and deposits cholesterol there. And that sets off a chronic inflammatory reaction, which helps lead plaque to build up in arteries.

Also people who inherit genes that raise their LDL have a higher risk of heart disease. That’s not true for people with genes that lower HDL, which is sometimes called good cholesterol.

And pretty much any class of drugs that reduces LDL, like statins, ezetimibe, PCSK-9 inhibitors, or resins like cholestyramine, also reduces heart disease.

Source: Nutrition Action Health Letter November 2017

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