Afternoon heart surgery may be safer than morning surgery. Patients who had open-heart surgery for aortic valve replacement in the afternoon had fewer heart attacks during surgery, and, over the next 500 days, fewer major adverse cardiac events, such as heart attack or heart failure.
In a separate study, those operated on in the afternoon had much lower levels of troponin, a measure of heart-muscle damage.
Possible reason: Natural circadian variations in the genetic mechanisms that protect tissue under stress.
Source: Bottom Line Personal February 2018 Barr Staels, PhD, professor of pharmacology, University of Lille, France, and senior author of two studies, one 596 patients and one of 88, published in The Lancet
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