For many children with advanced forms of neuroblastoma, receiving two separate stem cell transplants as part of their treatment is more beneficial than receiving one. That’s according to the results of an NCI-supported clinical trial conducted by the Children’s Oncology Group (COG).

Children in the trial had high-risk neuroblastoma, meaning that their tumors had features that make the cancer particularly aggressive and difficult to treat. Children who received two transplants separated by several weeks lived substantially longer without their cancer progressing or developing any other cancer-related problems, an outcome known as event-free survival, than children who underwent a single transplant, reported Julie Park, M.D., of Seattle Children’s Hospital, and her colleagues August 27 in JAMA.

Source: NCI