When breast cancer spreads to the bones (bone metastases), it can greatly affect quality of life. This somatic pain often responds to heat, or to mild pain relievers such as ibuprofen (Advil or Motrin), naproxen (Aleve or Naprosyn( or acetaminophen (Tylenol). Although you can get these medications without a prescription, check with your health care provider before taking them. There may be medical reasons you shouldn’t take these drugs. Opioids (such as morphine or oxycodone) can be added if the ibuprofen or acetaminophen alone doesn’t relieve the pain. You may also be given a bone-strengthening drug therapy to relieve the pain. These drugs are given once a month through an IV.
Source Susan G. Komen 2019